Clinical Cases:

Definition: Diseased condition resulted from ingestion of Contaminated food with Aflatoxin.

Characterized by:

• High mortality rate
• Retardation in growth

Cause:

- Aflatoxins: Potent chemical metabolites produced by certain toxogenic fungi (Aspergillus Flavus – Aspergillus parasiticus) under certain conditions include:

• Moisture content 14% or more in feed
• Temperature ranged from 20-30
• High relative humidity
• Bad storage condition

- Aflatoxins have four types (B1 – B2 – G1 – G2) B1 is the most toxigenic and carcinogenicز

Signs: Depend on (Dose – Species – Age – Duration of exposure )

Signs of Acute form:

• High mortality
• Retardation of growth
• Diarrhea containing undigested feed particles
• Paleness in comb and wattles
• Decrease egg production
• Decrease fertility and hatchability
• Nervous manifestation include (Ataxia – Staggering  gait – Opisotinous – Paralysis – Death with retracted head)

Signs of Chronic form:

• Retardation of growth
• Severe anemia
• Distended abdomen (Ascites)
• Diarrhea
• Low mortality
• Prolonged course

Control:

- No actual treatment of toxicated bird

- Supported treatment is essential procedure for control of Aflatoxicosis to increase vitality affected bird and reduce severity of lesions and this carried out by:

• Supply massive dose of Multivitamins (Vit. E – Vit. K – Vit. A – Selenium)
• Minerals as Calcium and Phosphorus to reduce fragility of bones
• Diuritics as Potassium Citrate to reduce renal dysfunction
• Liver stimulant as Heparenol to activate liver function
• Lipotrophic agent to mobilize and remove fat from liver in case of fatty liver
• Some antibiotics to reduce and suppress 2rd infection complications